CRISPRlnc: New lncRNA-specific SgRNA design method proposed

PHYSorg
Mar 7, 2024, 11:32 am177 pts
Long non-coding RNAs (lncRNAs) are non-protein-coding transcripts. Currently, CRISPR/Cas9 is a promising RNA-guided genome editing technology consisting of a Cas9 nuclease and a single-guide RNA (sgRNA). Considering the significant differences between lncRNAs and protein-coding genes, it is necessary to…

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