Nature

Nature, Published online: 09 April 2020; doi:10.1038/s41586-020-2223-yStructure of Mpro from COVID-19 virus and discovery of its inhibitors

Nature, Published online: 09 April 2020; doi:10.1038/d41586-020-01061-wBepiColombo is about to fly past Earth on its way to Mercury — but coronavirus precautions mean that most of its team will have to watch from home.

Nature, Published online: 09 April 2020; doi:10.1038/d41586-020-01075-4Mauro Ferrari leaves the European Research Council after three months.

Nature, Published online: 09 April 2020; doi:10.1038/d41586-020-01063-8Researchers warn production constraints and hoarding could limit SARS-CoV-2 vaccine supplies.

Nature, Published online: 09 April 2020; doi:10.1038/d41586-020-01056-7Doctors are reaching for drugs that dampen the immune response — but these also undermine the body’s own fight against the coronavirus.

Nature, Published online: 09 April 2020; doi:10.1038/d41586-020-01068-3US labs that underwent huge efforts to retool for COVID-19 testing still aren’t operating at full capacity. Experts say the lack of a national strategy is largely to blame.

Nature, Published online: 09 April 2020; doi:10.1038/d41586-020-01049-6Tantalizing signs that coronavirus lockdowns are making air cleaner aren’t as straightforward as they seem.

Nature, Published online: 09 April 2020; doi:10.1038/d41586-020-01066-5Springer Nature says it commits to offering researchers a route to publishing open access in Nature and most Nature-branded journals from 2021.

Nature, Published online: 09 April 2020; doi:10.1038/d41586-020-01060-xIn the face of COVID-19 restrictions on daily life, scientist-parents describe their efforts to balance family and work duties.

Nature, Published online: 09 April 2020; doi:10.1038/d41586-020-01008-1COVID-19’s lethality provides a grim opportunity to track its spread.

Nature, Published online: 08 April 2020; doi:10.1038/s41586-020-2188-xA human binary protein interactome map that includes around 53,000 protein–protein interactions involving more than 8,000 proteins provides a reference for the study of human cellular…

Nature, Published online: 08 April 2020; doi:10.1038/s41586-020-2175-2Analysis of genomic data from more than 60,000 cancer samples uncovers frequent multiple driver mutations in individual oncogenes, which confer enhanced oncogenicity in combination.

Nature, Published online: 08 April 2020; doi:10.1038/d41586-020-00853-4An uncertain outcome.

Nature, Published online: 08 April 2020; doi:10.1038/d41586-020-00975-9The timing of disruptions to biodiversity associated with global warming is a key, but little-explored, dimension of change. Will losses in biodiversity occur all at once, or be spread out…

Nature, Published online: 08 April 2020; doi:10.1038/s41586-020-2149-4Computer-aided engineering produces improvements to an enzyme that breaks down poly(ethylene terephthalate) (PET) into its constituent monomers, which are used to synthesize PET of…

Nature, Published online: 08 April 2020; doi:10.1038/s41586-020-2162-7Archaeological evidence that anthropic landscape changes and crop cultivation in southwestern Amazonia began about 10,000–11,000 years ago confirms that the region is a centre of early…

Nature, Published online: 08 April 2020; doi:10.1038/d41586-020-01046-9A squad of sensory cells in the throat prompts a reflex to keep the airways clear.

Nature, Published online: 08 April 2020; doi:10.1038/s41586-020-2141-zNaLi molecules are cooled to micro- and nanokelvin temperatures through collisions with ultracold Na atoms by using molecules and atoms in stretched hyperfine spin states and applying two…

Nature, Published online: 08 April 2020; doi:10.1038/s41586-020-2161-8Layered nanocomposites fabricated using a continuous and scalable process achieve properties exceeding those of natural nacre, the result of stiffened matrix polymer chains confined between…

Nature, Published online: 08 April 2020; doi:10.1038/s41586-020-2128-9Carbon dioxide enrichment of a mature forest resulted in the emission of the excess carbon back into the atmosphere via enhanced ecosystem respiration, suggesting that mature forests may be…

Nature, Published online: 08 April 2020; doi:10.1038/d41586-020-00962-0Will mature forests absorb enough carbon from the atmosphere to mitigate climate change as levels of carbon dioxide increase? An experiment in a eucalyptus forest provides fresh evidence.

Nature, Published online: 08 April 2020; doi:10.1038/s41586-020-2187-yIf early mitosis is too short, separase induces apoptosis by cleaving MCL2 and BCL-XL, thereby eliminating cells that are prone to chromosome missegregation.

Nature, Published online: 08 April 2020; doi:10.1038/d41586-020-01059-4If you struggle with home working but are having to do it because of the coronavirus, Lucy Taylor has some advice.

Nature, Published online: 08 April 2020; doi:10.1038/s41586-020-2189-9Using annual projections of temperature and precipitation to estimate when species will be exposed to potentially harmful climate conditions reveals that disruption of ecological assemblages…

Nature, Published online: 08 April 2020; doi:10.1038/s41586-020-2183-2Phosphorylation of INSIG1 and INSIG2 by PCK1 leads to a reduction in the binding of sterols, the activation of SREBP1 and SREBP2 and the downstream transcription of lipogenesis-associated…

Nature, Published online: 08 April 2020; doi:10.1038/d41586-020-00154-wUpdates on the respiratory illness that has infected more than one million people and killed tens of thousands.

Nature, Published online: 08 April 2020; doi:10.1038/s41586-020-2150-yA hexagonal (rather than cubic) alloy of silicon and germanium that has a direct (rather than indirect) bandgap emits light efficiently across a range of wavelengths, enabling electronic and…

Nature, Published online: 08 April 2020; doi:10.1038/d41586-020-00993-7The latest science news, in brief.

Nature, Published online: 08 April 2020; doi:10.1038/d41586-020-00502-wNature wades through the literature on COVID-19 so you don’t have to.

Nature, Published online: 08 April 2020; doi:10.1038/s41586-020-2167-2A population of neurons in the parabrachial nucleus that expresses prodynorphin monitors ingestion using mechanosensory signals from the upper digestive tract, and mediates negative feedback…