Revealing HIV drug-resistance mechanisms through protein structures

ScienceDaily
Jul 22, 2023, 4:47 am126 pts
Researchers have discovered the molecular mechanisms by which the human immunodeficiency virus (HIV) becomes resistant to Dolutegravir, one of the most effective, clinically used antiviral drugs for treating HIV. Their findings reveal how changes to the 3D structures of integrase, an HIV protein, can lead to…

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