Making therapeutic sense of antisense oligonucleotides

ScienceDaily
Jan 5, 2021, 9:56 am103 pts
Researchers have devised a molecular structural modification that boosts the efficacy of antisense oligonucleotide-based drugs by replacing the RNA strand of a heteroduplex oligonucleotide with DNA. This advance expands the scope and clinical applicability of nucleic-acid therapeutics across an ever-widening…

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