Drug discovery study identifies promising new compound to open constricted airways

ScienceDaily
Jan 4, 2021, 9:46 am110 pts
In a preclinical study, researchers identified and characterized 18 new compounds (agonists) that activate bitter taste receptor subtype TAS2R5 to promote relaxation of human airway smooth muscle cells. The cross-disciplinary team found 1,10 phenanthroline-5,6-dione (T5-8 for short) was 1,000 times more potent…

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