For CRISPR, tweaking DNA fragments before inserting yields highest efficiency rates yet

ScienceDaily
Dec 23, 2019, 12:29 pm55 pts
Researchers have now achieved the highest reported rates of inserting genes into human cells with the CRISPR-Cas9 gene-editing system, a necessary step for harnessing CRISPR for clinical gene-therapy applications. By chemically tweaking the ends of the DNA to be inserted, the new technique is up to five times…

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