Cas9 ancestor engineered into a compact genome editing tool

PHYSorg
May 15, 2025, 1:30 pm109 pts
Scientists at the McGovern Institute and the Broad Institute of MIT and Harvard have reengineered a compact RNA-guided enzyme they found in bacteria into an efficient, programmable editor of human DNA. The engineered protein, called NovaIscB, can be adapted to make precise changes to the genetic code, modulate…

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