First synthetic 'mini prion' shows how protein misfolding multiplies

PHYSorg
Apr 28, 2025, 3:00 pm252 ptsTop
Scientists at Northwestern University and University of California, Santa Barbara have created the first synthetic fragment of tau protein that acts like a prion. The "mini prion" folds and stacks into strands (or fibrils) of misfolded tau proteins, which then transmit their abnormally folded shape to other…

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