CRISPR-Cascade test detects bloodstream infections in minutes without amplification

PHYSorg
Mar 13, 2025, 11:30 am189 pts
University of Illinois at Urbana-Champaign researchers have developed a CRISPR-based diagnostic tool capable of detecting bloodstream infections in minutes without the need for nucleic acid amplification. The CRISPR-Cascade assay achieves attomolar sensitivity and incorporates an OR-gated logic function to…

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