NanoCas, a smaller version of CRISPR tested with a single AAV, delivers on-target results

PHYSorg
Feb 17, 2025, 10:50 am104 pts
Mammoth Biosciences researchers have developed NanoCas, an ultracompact CRISPR nuclease, demonstrating its ability to perform gene editing in non-liver tissues, including skeletal muscle, using a single adeno-associated virus (AAV) vector. Experiments in non-human primates (NHPs) resulted in editing…

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