Supercomputer simulation shows why beneficial mutations rarely lead to hypermutators in real organisms

PHYSorg
Feb 6, 2025, 10:21 am97 pts
In real life, mutants can arise when their DNA changes to give them an advantage over the rest of the population. A team from the University of Michigan has used simulations on the Pittsburgh Supercomputing Center's Neocortex system to find out why beneficial mutants rarely come to dominate real organisms.

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