Scientists report that buffer and pH strongly affect the phase separation of SARS-CoV-2 N protein

PHYSorg
Apr 8, 2024, 12:30 pm142 pts
In a new paper published in Molecular Biology of the Cell, the Allain lab (IBC) reported that the phase separation of the SARS-CoV-2 N protein strongly depends on the chosen buffer and pH. For example, the protonation of a single histidine side chain makes the difference if the protein phase separates or not.

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