New signaling pathway decoded in the decomposition of damaged lysosomes

PHYSorg
Apr 8, 2024, 10:34 am128 pts
Lysosomes are surrounded by a lipid bilayer that separates the acidic environment and the digestive enzymes of the organelle from the cytoplasm. Damage to this layer—lysosomal membrane permeabilization, or LMP for short—can trigger inflammation and even lead to cell death.

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