Anthrax lethal toxin and tumor necrosis factor-α synergize to induce mouse death

PHYSorg
Dec 27, 2023, 8:54 am431 ptsTop
Bacillus anthracis lethal toxin (LT) is a determinant of lethal anthrax. Its function in myeloid cells is required for bacterial dissemination, and LT itself can directly trigger dysfunction of the cardiovascular system. The interplay between LT and the host responses is important in the pathogenesis, but our…

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