How the epigenetic landscape modulates pioneer transcription factor binding

PHYSorg
May 24, 2023, 4:34 pm140 pts
Like thread tightly wrapped around a spool, DNA is wrapped around histones and packaged into structures called nucleosomes. Scientists at St. Jude Children's Research Hospital are exploring how a type of transcription factor called a pioneer transcription factor accesses DNA even when it is tightly wound. Their…

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